A mechanical, electrical dual autonomous self-healing multifunctional composite hydrogel.
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ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC8476776 | biostudies-literature |
REPOSITORIES: biostudies-literature
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Project description:Electrical tree growth in the insulation material is a main factor limiting the lifespan of insulation. A new method of increasing the durability and reliability of polymer dielectrics has been proposed by designing a three-phase electrical self-healing composite. SiO₂ micro and nano particles were loaded in the sample which can improve the resistance to electrical tree breakdown. Materials with hydrogen bonds were synthesized and added into epoxy matrix to make the composite self-healable. It is found that both SiO₂ and hydrogen-bonding self-healing material (HSM) can inhibit the electrical trees. Besides the self-healing behavior at the macro level, the incorporation of HSM can also make the micro defects such as electrical tree channel self-healable. The electrical self-healing composite will find a wide application in the field of electronic and electrical engineering.
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Project description:BackgroundWound healing has become a worldwide healthcare issue. Attempts in the area focus on developing patches with the capabilities of avoiding wound infection, promoting tissue remolding, and reporting treatment status that are of great value for wound treatment.ResultsIn this paper, we present a novel inverse opal film (IOF) patch based on a photo-crosslinking fish gelatin hydrogel with the desired features for wound healing and dynamic monitoring. The film with vibrant structure colors was constructed by using the mixture of fish gelatin methacryloyl, chitosan, and polyacrylic acid (PAA) to replicate colloidal crystal templates. As the structures of these natural biomolecules are well-retained during the fabrication, the resultant IOF was with brilliant biocompatibility, low immunogenicity, antibacterial property, as well as with the functions of promoting tissue growth and wound healing. In addition, the IOF presented interconnected nanopores and high specific surface areas for vascular endothelial growth factor loading, which could further improve its angiogenesis capability. More attractively, as the pH-responsive PAA was incorporated, the IOF patch could report the wound healing status through its real-time structural colors or reflectance spectra.ConclusionsThese features implied the practical value of the multifunctional fish gelatin hydrogel IOFs in clinical wound management.
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Project description:Conducting polymer hydrogels (CPHs) emerge as excellent functional materials, as they harness the advantages of conducting polymers with the mechanical properties and continuous 3D nanostructures of hydrogels. This bicomponent organization results in soft, all-organic, conducting micro-/nanostructures with multifarious material applications. However, the application of CPHs as functional materials for biomedical applications is currently limited due to the necessity to combine the features of biocompatibility, self-healing, and fine-tuning of the mechanical properties. To overcome this issue, we choose to combine a protected dipeptide as the supramolecular gelator, owing to its intrinsic biocompatibility and excellent gelation ability, with the conductive polymer polyaniline (PAni), which was polymerized in situ. Thus, a two-component, all-organic, conducting hydrogel was formed. Spectroscopic evidence reveals the formation of the emeraldine salt form of PAni by intrinsic doping. The composite hydrogel is mechanically rigid with a very high storage modulus ( G') value of ∼2 MPa, and the rigidity was tuned by changing the peptide concentration. The hydrogel exhibits ohmic conductivity, pressure sensitivity, and, importantly, self-healing features. By virtue of its self-healing property, the polymeric nonmetallic hydrogel can reinstate its intrinsic conductivity when two of its macroscopically separated blocks are rejoined. High cell viability of cardiomyocytes grown on the composite hydrogel demonstrates its noncytotoxicity. These combined attributes of the hydrogel allowed its utilization for dynamic range pressure sensing and as a conductive interface for electrogenic cardiac cells. The composite hydrogel supports cardiomyocyte organization into a spontaneously contracting system. The composite hydrogel thus has considerable potential for various applications.
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2022-01-01 | GSE165635 | GEO
Project description:Triboelectric nanogenerators (TENGs) have shown huge application potential in the fields of micro-nano energy harvesting and multifunctional sensing. However, the damage of triboelectric material is one of the challenges for their practical applications. Herein, we fabricated a flexible TENG employing self-healing hydrogel and fluorinated ethylene propylene film as triboelectric materials for mechanical energy harvesting and pressure monitoring. The prepared hydrogel not only has excellent flexibility, transparency, and self-healing property but also exhibits good mechanical property without plastic deformation and damage under a large stretchable strain of 200%. The output electric signals of TENGs are as high as 33.0 V and 3 μA under a contact frequency of 0.40 Hz and a pressure of 2.9 N, respectively, which can charge a capacitor of 0.22 μF to 24.3 V within 300 s. Note that the voltage retention rate of TENGs after self-healing is up to 88.0%. Moreover, hydrogel-based TENGs can act as a wearable pressure sensor for monitoring human motion, exhibiting a high sensitivity of 105.9 mV/N or 1.73 nA/N under a contact frequency of 0.40 Hz. This research provides a reference roadmap for designing TENGs and self-powered pressure sensors with flexibility, self-healing, and robustness.
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