Vector competence of Aedes aegypti and screening for differentially expressed microRNAs exposed to Zika virus.

ABSTRACT:

Background

Zika virus (ZIKV) is transmitted to humans primarily by Aedes aegypti. Previous studies on Ae. aegypti from Jiegao (JG) and Mengding (MD) in Yunnan province, China have shown that these mosquitoes are able to transmit ZIKV to their offspring through vertical transmission, indicating that these two Ae. aegypti strains pose a potential risk for ZIKV transmission. However, the vector competence of these two Ae. aegypti strains to ZIKV has not been evaluated and the molecular mechanisms influencing vector competence are still unclear.

Methods

Aedes aegypti mosquitoes from JG and MD were orally infected with ZIKV, and the infection rate (IR), dissemination rate (DR), transmission rate (TR) and transmission efficiency (TE) of these two mosquito strains were explored to

SUBMITTER: Zhu C 

PROVIDER: S-EPMC8477552 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature