A dosing algorithm for individualized radioiodine treatment of cats with hyperthyroidism.

ABSTRACT:

Background

Radioiodine (¹³¹ I) is the treatment of choice for hyperthyroidism in cats, but current ¹³¹ I-dosing protocols can induce iatrogenic hypothyroidism and expose azotemia.

Objectives

To develop a cat-specific algorithm to calculate the lowest ¹³¹ I dose to resolve hyperthyroidism, while minimizing risk of iatrogenic hypothyroidism and subsequent azotemia.

Animals

One thousand and four hundred hyperthyroid cats treated with ¹³¹ I.

Methods

Prospective case series (before-and-after study). All cats had serum concentrations of thyroxine (T₄ ), triiodothyronine (T₃ ), and thyroid-stimulating hormone (TSH) measured (off methimazole ≥1 week). Using thyroid scintigraphy, each cat's thyroid volume

SUBMITTER: Peterson ME 

PROVIDER: S-EPMC8478068 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature