Project description:This study investigates the role of Aldehyde Dehydrogenase 2 (ALDH2) in the pathogenesis of liver fibrosis. We performed gene expression profiling of liver tissues from wild-type (WT) and Aldh2 knockout mice subjected to a chronic fibrosis model. This dataset aims to identify molecular mechanisms and transcriptomic alterations associated with ALDH2 deficiency in the context of alcohol- and CCl4-induced liver fibrosis.

2026-07-05 | GSE317551 | GEO

Empagliflozin Ameliorates Aldehyde Dehydrogenase 2 Deficiency-induced Endothelial Dysfunction

Project description:We conducted RNA sequcing of the homozygous and heterozygous of ALDH2*2 by using human induced pluripotent stem cell-derived endothelial cells (hiPSC-ECs)

2023-03-30 | GSE184419 | GEO

Extramitochondrial Assembly of Mitochondrial Targeting Signal Disrupted Mitochondrial Enzyme Aldehyde Dehydrogenase.

Project description: Not available

| S-EPMC5906672 | biostudies-literature

Partially irreversible inactivation of mitochondrial aldehyde dehydrogenase by nitroglycerin.

Project description: Not available

| S-EPMC2576553 | biostudies-literature

Prospective study: Aldehyde dehydrogenase 2 gene is associated with cardio-cerebrovascular complications in type 2 diabetes patients.

Project description: Not available

| S-EPMC8504900 | biostudies-literature

The mitochondrial aldehyde dehydrogenase OsALDH2b negatively regulates tapetum degeneration in rice.

Project description: Not available