Adherence to Lipid-Lowering Treatment by Single-Pill Combination of Statin and Ezetimibe.

ABSTRACT:

Introduction

Although several studies have shown that a simplified cardiovascular drug treatment leads to better treatment adherence, limited and conflicting findings have been reported on the separate or single-pill combination of the now recommended association between a statin and ezetimibe. We addressed this issue in a large cohort of patients newly treated with statins to whom ezetimibe was additionally administered, either separately or as a single-pill combination.

Methods

A total of 256,012 patients (age 40-80 years) from the Lombardy Region (Italy) newly treated with statins during 2011-2013 were followed until 2018 to identify those to whom ezetimibe was added. The 2881 and 5351 patients who started a two-pill or a single-pill combination, respectively, of statin a

SUBMITTER: Rea F 

PROVIDER: S-EPMC8478750 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature