Ontology highlight
ABSTRACT:
SUBMITTER: Griffith LA
PROVIDER: S-EPMC8478992 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Griffith Lauren A LA Arnold Katherine M KM Sengers Bram G BG Tare Rahul S RS Houghton Franchesca D FD
Scientific reports 20210928 1
Articular cartilage functions as a shock absorber and facilitates the free movement of joints. Currently, there are no therapeutic drugs that promote the healing of damaged articular cartilage. Limitations associated with the two clinically relevant cell populations, human articular chondrocytes and mesenchymal stem cells, necessitate finding an alternative cell source for cartilage repair. Human embryonic stem cells (hESCs) provide a readily accessible population of self-renewing, pluripotent c ...[more]