IsoTV: processing and visualizing functional features of translated transcript isoforms.

ABSTRACT:

Summary

Despite the continuous discovery of new transcript isoforms, fueled by the recent increase in accessibility and accuracy of long-read RNA sequencing data, functional differences between isoforms originating from the same gene often remain obscure. To address this issue and enable researchers to assess potential functional consequences of transcript isoform variation on the proteome, we developed IsoTV. IsoTV is a versatile pipeline to process, predict and visualize the functional features of translated transcript isoforms. Attributes such as gene and isoform expression, transcript composition and functional features are summarized in an easy-to-interpret visualization. IsoTV is able to analyze a variety of data types from all eukaryotic organisms, including short- and long-

SUBMITTER: Annaldasula S 

PROVIDER: S-EPMC8479675 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature