Does the Anti-Mullerian Hormone Decline Rate Improve the Prediction of Age at Menopause?

ABSTRACT:

Objectives

There are controversial studies investigating whether multiple anti-Mullerian hormone (AMH) measurements can improve the individualized prediction of age at menopause in the general population. This study aimed to reexplore the additive role of the AMH decline rate in single AMH measurement for improving the prediction of age at physiological menopause, based on two common statistical models for analysis of time-to-event data, including time-dependent Cox regression and Cox proportional-hazards regression models.

Methods

A total of 901 eligible women, aged 18-50 years, were recruited from the Tehran Lipid and Glucose Study (TLGS) population and followed up every 3 years for 18 years. The serum AMH level was measured at the time of recruitment and twice after recru

SUBMITTER: Ramezani Tehrani F 

PROVIDER: S-EPMC8481767 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature