Ontology highlight
ABSTRACT:
SUBMITTER: Khade RL
PROVIDER: S-EPMC8482462 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Khade Rahul L RL Abucayon Erwin G EG Powell Douglas R DR Richter-Addo George B GB Zhang Yong Y
ACS omega 20210915 38
NO is well-known for its <i>trans</i> effect. NO binding to ferrous hemes of the form (por)Fe(L) (L = neutral N-based ligand) to give the {FeNO}<sup>7</sup> (por)Fe(NO)(L) product results in a lengthening of the axial <i>trans</i> Fe-L bond. In contrast, NO binding to the ferric center in [(por)Fe(L)]<sup>+</sup> to give the {FeNO}<sup>6</sup> [(por)Fe(NO)(L)]<sup>+</sup> product results in a shortening of the <i>trans</i> Fe-L bond. NO binding to both ferrous and ferric centers involves the low ...[more]