Gallbladder squamous cell carcinoma: An analysis of 1084 cases from the National Cancer Database.

ABSTRACT:

Background/objectives

Gallbladder squamous cell carcinoma (SCC) is an uncommon malignancy whose rarity has made it particularly challenging to study. We utilized a national database to shed light on the clinicopathologic characteristics, management patterns, and survival associated with these tumors.

Methods

Patients with gallbladder SCC were identified in the National Cancer Database. Clinicopathologic and treatment characteristics were recorded and compared with adenocarcinoma for context. Univariate and multivariable survival analyses were completed for patients who underwent resection.

Results

Overall, 1084 patients with SCC and 23 958 patients with adenocarcinoma were identified. Compared with those with adenocarcinoma, patients with SCC had higher grade tumors (

SUBMITTER: Ayabe RI 

PROVIDER: S-EPMC8482609 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature