Is pulmonary embolism recurrence linked with the severity of the first event? A French retrospective cohort study.

ABSTRACT:

Objectives

Severity of a first pulmonary embolism (PE) is sometimes proposed as a criterion for prolonging anticoagulant treatment. However, little evidence supports this idea. We attempted to determine the connection between severity of first PE and the risk of recurrence.

Participants

Patients admitted with PE between 2012 and 2018 and for whom anticoagulant treatment had been discontinued were followed. PEs were classified according to the severity into the following two groups: those with associated cardiac involvement (increased cardiac biomarker(s) and/or echocardiographic right ventricular dysfunction) and those with no cardiac involvement which were classified as non-severe. Recurrence-free survivals were estimated using the Kaplan-Meier method and compared using the

SUBMITTER: Ferrari E 

PROVIDER: S-EPMC8483023 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature