Plasma Metabolomic Signatures of Healthy Dietary Patterns in the Chronic Renal Insufficiency Cohort (CRIC) Study.

ABSTRACT:

Background

In individuals with chronic kidney disease (CKD), healthy dietary patterns are inversely associated with CKD progression. Metabolomics, an approach that measures many small molecules in biofluids, can identify biomarkers of healthy dietary patterns.

Objectives

We aimed to identify known metabolites associated with greater adherence to 4 healthy dietary patterns in CKD patients.

Methods

We examined associations between 486 known plasma metabolites and Healthy Eating Index (HEI)-2015, Alternative Healthy Eating Index (AHEI)-2010, the Dietary Approaches to Stop Hypertension (DASH) diet, and alternate Mediterranean diet (aMED) in 1056 participants (aged 21-74 y at baseline) in the Chronic Renal Insufficiency Cohort (CRIC) Study. Usual dietary intake was assesse

SUBMITTER: Kim H 

PROVIDER: S-EPMC8485904 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature