Old age and other factors associated with salivary microbiome variation.

ABSTRACT:

Background

Many factors can contribute to the exact makeup of the salivary microbiome. Differences in the oral microbiome occur with old age, which may be due to oral conditions and diseases associated with old age, such as edentulism, as well as other unknown causes.

Methods

The salivary microbiome was sampled in patients from a large urban clinic. For all subjects age, gender, periodontal status, caries status, presence of edentulism, medications, and tobacco usage were recorded. Multifactor analysis was used to study variation in salivary microbiome profiles linked to these factors.

Results

In the population sampled, there were significantly higher numbers of edentulous subjects, and increased levels of polypharmacy found with aging. Large differences in alpha dive

SUBMITTER: Schwartz JL 

PROVIDER: S-EPMC8489047 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature