Prostatic calcifications: Quantifying occurrence, radiodensity, and spatial distribution in prostate cancer patients.

ABSTRACT:

Background

To evaluate the prevalence, density, and distribution of prostate calcification in patients with prostate cancer.

Methods

Patients who underwent both Gallium-68 PSMA PET/CT and MRI of the prostate over the course of a year were selected for analysis. The CT images with visible calcifications within the prostate were included and calcifications automatically isolated using a threshold of 130 HU. The corresponding multiparametric MRI was assessed and the peripheral zone, transition zone, MRI-visible tumor, and urethra manually contoured. The contoured MRI and CT images were registered using rigid registration, and calcifications mapped automatically to the MRI contours.

Results

A total of 85 men (age range 50-88, mean 69 years, standard deviation 7.2 years) w

SUBMITTER: Singh S 

PROVIDER: S-EPMC8492071 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature