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Skeletal manifestations of congenital syphilis: Rare but clinically relevant.


ABSTRACT: Congenital syphilis occurs as a result of maternal transmission of treponema pallidum in utero. This condition is mainly diagnosed by treponemal and non-treponemal serologic tests. However, both maternal nontreponemal and treponemal IgG antibodies can be transferred through the placenta to the fetus, thus complicating its interpretation soon after birth. We report a case of a neonate with congenital syphilis whose mother became infected after the first trimester of pregnancy. We report how skeletal radiographs expedite the clinical decision-making process and direct further management of neonates. This case also highlights the need for repeated syphilis screening in the latter part of pregnancy.

SUBMITTER: Pg Mohammad Hussein PMN 

PROVIDER: S-EPMC8495030 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Skeletal manifestations of congenital syphilis: Rare but clinically relevant.

Pg Mohammad Hussein Pg Mohammad Nizam PMN   Kew Seih Teck ST   Nang Khin Mya KM   Kadir Fairrul F   Teh Yong Guang YG  

Radiology case reports 20211001 12


Congenital syphilis occurs as a result of maternal transmission of <i>treponema pallidum</i> in utero. This condition is mainly diagnosed by treponemal and non-treponemal serologic tests. However, both maternal nontreponemal and treponemal IgG antibodies can be transferred through the placenta to the fetus, thus complicating its interpretation soon after birth. We report a case of a neonate with congenital syphilis whose mother became infected after the first trimester of pregnancy. We report ho  ...[more]

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