Ontology highlight
ABSTRACT:
SUBMITTER: Klaas M
PROVIDER: S-EPMC8495264 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Klaas Mariliis M Mäemets-Allas Kristina K Heinmäe Elizabeth E Lagus Heli H Cárdenas-León Claudia Griselda CG Arak Terje T Eller Mart M Kingo Külli K Kankuri Esko E Jaks Viljar V
Frontiers in cell and developmental biology 20210923
Thrombospondin-4 (THBS4) is a non-structural extracellular matrix molecule associated with tissue regeneration and a variety of pathological processes characterized by increased cell proliferation and migration. However, the mechanisms of how THBS4 regulates cell behavior as well as the pathways contributing to its effects have remained largely unexplored. In the present study we investigated the role of THBS4 in skin regeneration both <i>in vitro</i> and <i>in vivo</i>. We found that THBS4 expr ...[more]