Ontology highlight
ABSTRACT:
SUBMITTER: Nohr AK
PROVIDER: S-EPMC8496226 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Nøhr Anne Krogh AK Hanghøj Kristian K Garcia-Erill Genís G Li Zilong Z Moltke Ida I Albrechtsen Anders A
G3 (Bethesda, Md.) 20210801 8
Estimation of relatedness between pairs of individuals is important in many genetic research areas. When estimating relatedness, it is important to account for admixture if this is present. However, the methods that can account for admixture are all based on genotype data as input, which is a problem for low-depth next-generation sequencing (NGS) data from which genotypes are called with high uncertainty. Here, we present a software tool, NGSremix, for maximum likelihood estimation of relatednes ...[more]