The Urinary Microbiome in Postmenopausal Women with Recurrent Urinary Tract Infections.

ABSTRACT:

Purpose

The etiology of postmenopausal recurrent urinary tract infection (UTI) is not completely known, but the urinary microbiome is thought to be implicated. We compared the urinary microbiome in menopausal women with recurrent UTIs to age-matched controls, both in the absence of acute infection.

Materials and methods

This is a cross-sectional analysis of baseline data from 64 women enrolled in a longitudinal cohort study. All women were using topically applied vaginal estrogen. Women >55 years of age from the following groups were enrolled: 1) recurrent UTIs on daily antibiotic prophylaxis, 2) recurrent UTIs not on antibiotic prophylaxis and 3) age-matched controls without recurrent UTIs. Catheterized urine samples were collected at least 4 weeks after last treatment for

SUBMITTER: Vaughan MH 

PROVIDER: S-EPMC8497440 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature