Ontology highlight
ABSTRACT:
SUBMITTER: Zhou W
PROVIDER: S-EPMC8499914 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Zhou Wenyang W Xu Chang C Wang Pingping P Anashkina Anastasia A AA Jiang Qinghua Q
Briefings in bioinformatics 20220101 1
Since the outbreak of SARS-CoV-2, the etiologic agent of the COVID-19 pandemic, the viral genome has acquired numerous mutations with the potential to alter the viral infectivity and antigenicity. Part of mutations in SARS-CoV-2 spike protein has conferred virus the ability to spread more quickly and escape from the immune response caused by the monoclonal neutralizing antibody or vaccination. Herein, we summarize the spatiotemporal distribution of mutations in spike protein, and present recent ...[more]