Lower plasma calcium associated with COVID-19, but not with disease severity: a two-centre retrospective cohort study.

ABSTRACT:

Background

Previous studies indicate hypocalcaemia as a potential diagnostic and prognostic marker of corona-virus disease 2019 (COVID-19). Our aim was to investigate these relations in more detail in a large test cohort and an independent validation cohort.

Methods

We retrospectively included 2792 COVID-19 suspected patients that presented to the emergency department (ED) of two hospitals. Plasma calcium and ionized plasma calcium levels were compared between COVID-19 positive and negative patients, and between severe and non-severe COVID-19 patients using univariate and multivariate analyses in the first hospital (N = 1363). Severe COVID-19 was defined as intensive care unit (ICU) admission or death within 28 d after admission. The results were validated by repeatin

SUBMITTER: Deodatus JA 

PROVIDER: S-EPMC8500306 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature