Ontology highlight
ABSTRACT: Background/objectives
Accurate estimates of clinically important difference (CID) are required for interpreting the clinical importance of treatments to improve physical function, but CID estimates vary in different disease populations. We determined the CID for two common measures of walking ability in mobility-limited older men.Design
Longitudinal, multisite placebo-controlled trial.Setting/participants
Men enrolled in the Testosterone Trials who had self-reported mobility limitation and gait speed less than 1.2 m/second (n = 429). Testosterone- and placebo-allocated participants were combined for this study.Results
Mean changes from baseline, adjusting for time-in-intervention and site, were 29.6, 13.2, 12.5, -2.4, and -32.6 m for 6MWD, and 15.4, 7.2, 2.1
SUBMITTER: Stephens-Shields AJ
PROVIDER: S-EPMC8500528 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature