ASHLEYS: automated quality control for single-cell Strand-seq data.
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ABSTRACT: Summary
Single-cell DNA template strand sequencing (Strand-seq) enables chromosome length haplotype phasing, construction of phased assemblies, mapping sister-chromatid exchange events and structural variant discovery. The initial quality control of potentially thousands of single-cell libraries is still done manually by domain experts. ASHLEYS automates this tedious task, delivers near-expert performance and labels even large data sets in seconds.Availability and implementation
github.com/friendsofstrandseq/ashleys-qc, MIT license.Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Eimer C
PROVIDER: S-EPMC8504637 | biostudies-literature |
REPOSITORIES: biostudies-literature
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