Prenatal Maternal Bereavement and Its Association With Intellectual Disability in the Offspring.

ABSTRACT:

Objective

This study aimed to examine the association of a mother's loss of a close relative before or during pregnancy with intellectual disability (ID) in the offspring.

Methods

We performed a nationwide population-based cohort study based on Danish national registries. All live-born singletons born in Denmark during the 1978-2016 period (n = 2,216,601) were followed up starting from birth to 38 years of age. Log-linear Poisson regression was used to estimate the association between maternal bereavement (the death of an older child, a partner, or a parent 1 year before or during pregnancy) and the risk of ID in the offspring.

Results

Maternal bereavement during or before pregnancy was associated with an increased risk of ID (incidence rate ratio [IRR] = 1.15; 95% co

SUBMITTER: Su X 

PROVIDER: S-EPMC8505139 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature