Ontology highlight
ABSTRACT:
SUBMITTER: Smith ER
PROVIDER: S-EPMC85086 | biostudies-literature | 2000 Jan
REPOSITORIES: biostudies-literature
Molecular and cellular biology 20000101 1
In Drosophila, dosage compensation-the equalization of most X-linked gene products in males and females-is achieved by a twofold enhancement of the level of transcription of the X chromosome in males relative to each X chromosome in females. A complex consisting of at least five gene products preferentially binds the X chromosome at numerous sites in males and results in a significant increase in the presence of a specific histone isoform, histone 4 acetylated at lysine 16. Recently, RNA transcr ...[more]