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ABSTRACT: Objective
To systematically review the conduct and reporting of formula trials.Design
Systematic review.Data sources
Medline, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) were searched from 1 January 2006 to 31 December 2020.Review methods
Intervention trials comparing at least two formula products in children less than three years of age were included, but not trials of human breast milk or fortifiers of breast milk. Data were extracted in duplicate and primary outcome data were synthesised for meta-analysis with a random effects model weighted by the inverse variance method. Risk of bias was evaluated with Cochrane risk of bias version 2.0, and risk of undermining breastfeeding was evaluated according to published consensus guidance
SUBMITTER: Helfer B
PROVIDER: S-EPMC8513520 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature