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The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review.


ABSTRACT: Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses. This review focuses on outlining the stimulatory as well as the inhibitory effects of heat-shock proteins 27, 40, 70, 65, 60, and 90 in experimental and clinical autoimmune settings.

SUBMITTER: Androvitsanea A 

PROVIDER: S-EPMC8533860 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature

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The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review.

Androvitsanea Ariadni A   Stylianou Kostas K   Drosataki Eleni E   Petrakis Ioannis I  

Cells 20211001 10


Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses. This review focuses on outlining the stimulatory as well as the inhibitory effects of heat-shock proteins 27, 40, 70, 65, 60, and 90 in experimental and clinical autoimmune settings. ...[more]

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