Ontology highlight
ABSTRACT:
SUBMITTER: Cheng H
PROVIDER: S-EPMC8538656 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Cheng Hao H Zhang Feng F Ding Yang Y
Pharmaceutics 20211009 10
The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein 9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform for gene correction, transcriptional regulation, disease modeling, and nucleic acids imaging. However, the insufficient transfection and off-target risks have seriously hampered the potential biomedical applications of CRISPR/Cas9 technology. Herein, we review the recent progress towards CRISPR/Cas9 system delivery based ...[more]