Regional contributions to left ventricular stroke volume determined by cardiac magnetic resonance imaging in cardiac resynchronization therapy.

ABSTRACT:

Background

Cardiac resynchronization therapy (CRT) restores ventricular synchrony and induces left ventricular (LV) reverse remodeling in patients with heart failure (HF) and dyssynchrony. However, 30% of treated patients are non-responders despite all efforts. Cardiac magnetic resonance imaging (CMR) can be used to quantify regional contributions to stroke volume (SV) as potential CRT predictors. The aim of this study was to determine if LV longitudinal (SV_long%), lateral (SV_lat%), and septal (SV_sept%) contributions to SV differ from healthy controls and investigate if these parameters can predict CRT response.

Methods

Sixty-five patients (19 women, 67 ± 9 years) with symptomatic HF (LVEF ≤ 35%) and broadened QRS (≥ 120 ms) underwent CMR. SV

SUBMITTER: Ostenson B 

PROVIDER: S-EPMC8549254 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature