Clinical characteristics and prognosis of immunosuppressed inpatients with COVID-19 in Japan.

ABSTRACT:

Introduction

We aimed to analyze the clinical characteristics and outcomes of immunosuppressed inpatients with coronavirus disease 2019 (COVID-19).

Methods

In this observational study, we utilized a large nationwide registry of hospitalized patients with COVID-19 in Japan. Patients' baseline characteristics and outcomes were compared according to the immunosuppressed states of the patients. The impact of different therapeutic agents on the clinical courses of the patients was evaluated.

Results

Data of 14,760 patients were included, and 887 (5.9%) were immunosuppressed. The immunosuppressed state of the patient resulted from solid tumor (43.3%, n = 384), chemotherapy within 3 months (15.6%, n = 138), collagen disease (16.9%, n = 150), use of immunosuppressive agents (

SUBMITTER: Nomoto H 

PROVIDER: S-EPMC8552558 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature