A cis-regulatory element promoting increased transcription at low temperature in cultured ectothermic Drosophila cells.

ABSTRACT:

Background

Temperature change affects the myriad of concurrent cellular processes in a non-uniform, disruptive manner. While endothermic organisms minimize the challenge of ambient temperature variation by keeping the core body temperature constant, cells of many ectothermic species maintain homeostatic function within a considerable temperature range. The cellular mechanisms enabling temperature acclimation in ectotherms are still poorly understood. At the transcriptional level, the heat shock response has been analyzed extensively. The opposite, the response to sub-optimal temperature, has received lesser attention in particular in animal species. The tissue specificity of transcriptional responses to cool temperature has not been addressed and it is not clear whether a prominent

SUBMITTER: Bai Y 

PROVIDER: S-EPMC8555087 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature