Prophage carriage as a molecular epidemiological marker in Streptococcus pneumoniae.
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ABSTRACT:
SUBMITTER: Severina E
PROVIDER: S-EPMC85553 | biostudies-literature | 1999 Oct
REPOSITORIES: biostudies-literature
Publications
Prophage carriage as a molecular epidemiological marker in Streptococcus pneumoniae.
Severina E E Ramirez M M Tomasz A A
Journal of clinical microbiology 19991001 10
The great majority of clinical isolates of Streptococcus pneumoniae carry prophages that may be identified through their hybridization with a DNA probe specific for the pneumococcal lytA gene (M. Ramirez, E. Severina, and A. Tomasz, J. Bacteriol. 181:3618-3625, 1999). We now show that the lytA hybridization pattern of chromosomal SmaI digests is stable for a given strain during extensive serial culturing in the laboratory; the pattern is specific for the strain's clonal type, as defined by pulse ...[more]
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