Ontology highlight
ABSTRACT:
SUBMITTER: Dupont L
PROVIDER: S-EPMC8556155 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Dupont Liane L Snell Luke B LB Graham Carl C Seow Jeffrey J Merrick Blair B Lechmere Thomas T Maguire Thomas J A TJA Hallett Sadie R SR Pickering Suzanne S Charalampous Themoula T Alcolea-Medina Adela A Huettner Isabella I Jimenez-Guardeño Jose M JM Acors Sam S Almeida Nathalia N Cox Daniel D Dickenson Ruth E RE Galao Rui Pedro RP Kouphou Neophytos N Lista Marie Jose MJ Ortega-Prieto Ana Maria AM Wilson Harry H Winstone Helena H Fairhead Cassandra C Su Jia Zhe JZ Nebbia Gaia G Batra Rahul R Neil Stuart S Shankar-Hari Manu M Edgeworth Jonathan D JD Malim Michael H MH Doores Katie J KJ
Nature microbiology 20211015 11
COVID-19 vaccine design and vaccination rollout need to take into account a detailed understanding of antibody durability and cross-neutralizing potential against SARS-CoV-2 and emerging variants of concern (VOCs). Analyses of convalescent sera provide unique insights into antibody longevity and cross-neutralizing activity induced by variant spike proteins, which are putative vaccine candidates. Using sera from 38 individuals infected in wave 1, we show that cross-neutralizing activity can be de ...[more]