Rumen-protected glucose supplementation in transition dairy cows shifts fermentation patterns and enhances mucosal immunity.

ABSTRACT: Manipulation of perinatal diets, such as supplementing feed with rumen-protected glucose (RPG), has been positively regarded as a strategy to improve milking performance. This study was conducted to assess the effects of RPG on the fermentation profiles, resident microbiota and mucosal immunity in the cecum. Ten Holstein dairy cows were randomly assigned to either a 25 g/kg RPG diet (DM basis) or a 11 g/kg coating fat diet (control, CON). Compared with the CON group, the acetate-to-propionate ratio was lower in the RPG group. Gene expression analysis indicated that RPG supplementation tended to upregulate the expression of Na⁺/H⁺ hydrogen exchanger 3 (NHE3) (P = 0.076). RPG supplementation downregulated the expression of genes involved in self-rehabilita

SUBMITTER: Zhang X 

PROVIDER: S-EPMC8556486 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature