Sleep medication use and risk of fractures in breast cancer survivors.

ABSTRACT:

Purpose

Sleep problems are more common in breast cancer survivors than those without a cancer history. Our goal was to examine the risk of fractures among breast cancers survivors who used prescription sleep aids.

Methods

We conducted a retrospective cohort study of 21,346 adult women diagnosed with stage 0-III breast cancer between 2009 and 2016 and followed them through 2017. We examined person-year rates of fractures by sleep medication use and calculated adjusted hazard ratios (HR) and 95% confidence intervals (CI) with Cox proportional hazards models using time-dependent variables for sleep medications and covariate medications (antidepressants, anti-anxiety medications, and bisphosphonates) adjusted for demographics, comorbidities, and tumor characteristics and cancer

SUBMITTER: Haque R 

PROVIDER: S-EPMC8558269 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature