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ABSTRACT: Background
The Cholera Hospital-Based Intervention for 7 Days (CHoBI7) mobile health (mHealth) program was a cluster-randomized controlled trial of diarrhea patient households conducted in Dhaka, Bangladesh.Methods
Patients were block-randomized to 3 arms: standard message on oral rehydration solution use; health facility delivery of CHoBI7 plus mHealth (no home visits); and health facility delivery of CHoBI7 plus 2 home visits and mHealth. The primary outcome was reported diarrhea in the past 2 weeks collected monthly for 12 months. The secondary outcomes were stunting, underweight, and wasting at a 12-month follow-up. Analysis was intention-to-treat.Results
Between 4 December 2016 and 26 April 2018, 2626 participants in 769 households were randomly allocated to 3 arms: 849 participants to the standard message arm, 886 to mHealth with no home visits arm, and 891 to the mHealth with 2 home visits. Children <5 years had significantly lower 12-month diarrhea prevalence in both the mHealth with 2 home visits arm (prevalence ratio [PR]: 0.73 [95% confidence interval {CI}, .61-.87]) and the mHealth with no home visits arm (PR: 0.82 [95% CI, .69-.97]). Children <2 years were significantly less likely to be stunted in both the mHealth with 2 home visits arm (33% vs 45%; odds ratio [OR]: 0.55 [95% CI, .31-.97]) and the mHealth with no home visits arm (32% vs 45%; OR: 0.54 [95% CI, .31-.96]) compared with children in the standard message arm.Conclusions
The CHoBI7 mHealth program lowered pediatric diarrhea and stunting among diarrhea patient households.Clinical trials registration
NCT04008134.
SUBMITTER: George CM
PROVIDER: S-EPMC8563223 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
George Christine Marie CM Monira Shirajum S Zohura Fatema F Thomas Elizabeth D ED Hasan M Tasdik MT Parvin Tahmina T Hasan Khaled K Rashid Mahamud-Ur MU Papri Nowshin N Islam Aminul A Rahman Zillur Z Rafique Raisa R Islam Bhuyian Md Sazzadul MS Saxton Ronald R Labrique Alain A Alland Kelsey K Barman Indrajeet I Jubyda Fatema Tuz FT Afroze Farzana F Sultana Marzia M Johura Fatema-Tuz FT Khan Md Abul Hasem MAH Tahmina Sanya S Munmun Farzana F Sack David A DA Perin Jamie J Alam Munirul M
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20211101 9
<h4>Background</h4>The Cholera Hospital-Based Intervention for 7 Days (CHoBI7) mobile health (mHealth) program was a cluster-randomized controlled trial of diarrhea patient households conducted in Dhaka, Bangladesh.<h4>Methods</h4>Patients were block-randomized to 3 arms: standard message on oral rehydration solution use; health facility delivery of CHoBI7 plus mHealth (no home visits); and health facility delivery of CHoBI7 plus 2 home visits and mHealth. The primary outcome was reported diarrh ...[more]