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Effects of a Water, Sanitation, and Hygiene Mobile Health Program on Diarrhea and Child Growth in Bangladesh: A Cluster-randomized Controlled Trial of the Cholera Hospital-based Intervention for 7 Days (CHoBI7) Mobile Health Program.


ABSTRACT:

Background

The Cholera Hospital-Based Intervention for 7 Days (CHoBI7) mobile health (mHealth) program was a cluster-randomized controlled trial of diarrhea patient households conducted in Dhaka, Bangladesh.

Methods

Patients were block-randomized to 3 arms: standard message on oral rehydration solution use; health facility delivery of CHoBI7 plus mHealth (no home visits); and health facility delivery of CHoBI7 plus 2 home visits and mHealth. The primary outcome was reported diarrhea in the past 2 weeks collected monthly for 12 months. The secondary outcomes were stunting, underweight, and wasting at a 12-month follow-up. Analysis was intention-to-treat.

Results

Between 4 December 2016 and 26 April 2018, 2626 participants in 769 households were randomly allocated to 3 arms: 849 participants to the standard message arm, 886 to mHealth with no home visits arm, and 891 to the mHealth with 2 home visits. Children <5 years had significantly lower 12-month diarrhea prevalence in both the mHealth with 2 home visits arm (prevalence ratio [PR]: 0.73 [95% confidence interval {CI}, .61-.87]) and the mHealth with no home visits arm (PR: 0.82 [95% CI, .69-.97]). Children <2 years were significantly less likely to be stunted in both the mHealth with 2 home visits arm (33% vs 45%; odds ratio [OR]: 0.55 [95% CI, .31-.97]) and the mHealth with no home visits arm (32% vs 45%; OR: 0.54 [95% CI, .31-.96]) compared with children in the standard message arm.

Conclusions

The CHoBI7 mHealth program lowered pediatric diarrhea and stunting among diarrhea patient households.

Clinical trials registration

NCT04008134.

SUBMITTER: George CM 

PROVIDER: S-EPMC8563223 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Publications

Effects of a Water, Sanitation, and Hygiene Mobile Health Program on Diarrhea and Child Growth in Bangladesh: A Cluster-randomized Controlled Trial of the Cholera Hospital-based Intervention for 7 Days (CHoBI7) Mobile Health Program.

George Christine Marie CM   Monira Shirajum S   Zohura Fatema F   Thomas Elizabeth D ED   Hasan M Tasdik MT   Parvin Tahmina T   Hasan Khaled K   Rashid Mahamud-Ur MU   Papri Nowshin N   Islam Aminul A   Rahman Zillur Z   Rafique Raisa R   Islam Bhuyian Md Sazzadul MS   Saxton Ronald R   Labrique Alain A   Alland Kelsey K   Barman Indrajeet I   Jubyda Fatema Tuz FT   Afroze Farzana F   Sultana Marzia M   Johura Fatema-Tuz FT   Khan Md Abul Hasem MAH   Tahmina Sanya S   Munmun Farzana F   Sack David A DA   Perin Jamie J   Alam Munirul M  

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20211101 9


<h4>Background</h4>The Cholera Hospital-Based Intervention for 7 Days (CHoBI7) mobile health (mHealth) program was a cluster-randomized controlled trial of diarrhea patient households conducted in Dhaka, Bangladesh.<h4>Methods</h4>Patients were block-randomized to 3 arms: standard message on oral rehydration solution use; health facility delivery of CHoBI7 plus mHealth (no home visits); and health facility delivery of CHoBI7 plus 2 home visits and mHealth. The primary outcome was reported diarrh  ...[more]

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