Ontology highlight
ABSTRACT:
SUBMITTER: Lupala CS
PROVIDER: S-EPMC8565036 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Lupala Cecylia Severin CS Kumar Vikash V Su Xiao-Dong XD Wu Chun C Liu Haiguang H
Computers in biology and medicine 20211103
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the COVID-19 pandemic. Angiotensin-converting enzyme 2 (ACE2) has been identified as the host cell receptor that binds to the receptor-binding domain (RBD) of the SARS-COV-2 spike protein and mediates cell entry. Because the ACE2 proteins are widely available in mammals, it is important to investigate the interactions between the RBD and the ACE2 of other mammals. Here we analyzed the sequences of ACE2 pro ...[more]