Ontology highlight
ABSTRACT:
SUBMITTER: Wen XM
PROVIDER: S-EPMC8566372 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Wen Xiang-Mei XM Xu Zi-Jun ZJ Jin Ye Y Xia Pei-Hui PH Ma Ji-Chun JC Qian Wei W Lin Jiang J Qian Jun J
Frontiers in immunology 20211021
Acute myeloid leukemia (AML) is a heterogeneous disease related to a broad spectrum of molecular alterations. The successes of immunotherapies treating solid tumors and a deeper understanding of the immune systems of patients with hematologic malignancies have promoted the development of immunotherapies for the treatment of AML. And high tumor mutational burden (TMB) is an emerging predictive biomarker for response to immunotherapy. However, the association of gene mutation in AML with TMB and i ...[more]