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Silylboronate-Mediated Defluorosilylation of Aryl Fluorides with or without Ni-Catalyst

ABSTRACT: The defluorosilylation of aryl fluorides to access aryl silanes was achieved under transition-metal-free conditions via an inert C–F bond activation. The defluorosilylation, mediated by silylboronates and KOtBu, proceeded smoothly at room temperature to afford various aryl silanes in good yields. Although a comparative experiment indicated that Ni catalyst facilitated this transformation more efficiently, the transition-metal-free protocol is advantageous from a green chemistry perspective.

SUBMITTER: Zhou J

PROVIDER: S-EPMC8573161 | biostudies-literature |

REPOSITORIES: biostudies-literature

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