Plasma Hydrogen Sulfide Is Positively Associated With Post-operative Survival in Patients Undergoing Surgical Revascularization.

ABSTRACT: Objective: Hydrogen sulfide (H₂S) is a gaseous signaling molecule and redox factor important for cardiovascular function. Deficiencies in its production or bioavailability are implicated in atherosclerotic disease. However, it is unknown if circulating H₂S levels differ between vasculopaths and healthy individuals, and if so, whether H₂S measurements can be used to predict surgical outcomes. Here, we examined: (1) Plasma H₂S levels in patients undergoing vascular surgery and compared these to healthy controls, and (2) the association between H₂S levels and mortality in a cohort of patients undergoing surgical revascularization. Methods: One hundred and fifteen patients undergoing carotid endarterectomy, open lower extremi

SUBMITTER: Longchamp A 

PROVIDER: S-EPMC8574965 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature