Validation of a spatial agent-based model for Taenia solium transmission ("CystiAgent") against a large prospective trial of control strategies in northern Peru.

ABSTRACT:

Background

The pork tapeworm (Taenia solium) is a parasitic helminth that imposes a major health and economic burden on poor rural populations around the world. As recognized by the World Health Organization, a key barrier for achieving control of T. solium is the lack of an accurate and validated simulation model with which to study transmission and evaluate available control and elimination strategies. CystiAgent is a spatially-explicit agent based model for T. solium that is unique among T. solium models in its ability to represent key spatial and environmental features of transmission and simulate spatially targeted interventions, such as ring strategy.

Methods/principal findings

We validated CystiAgent against results from the Ring Strategy Trial (RST)-a large cluster-r

SUBMITTER: Pray IW 

PROVIDER: S-EPMC8575314 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature