Association between metabolic syndrome components and the risk of developing nephrolithiasis: A systematic review and bayesian meta-analysis.

ABSTRACT: Background: There is increasing evidence that nephrolithiasis is a systemic disease, as opposed to an isolated urinary metabolic problem, after considerable links were found between nephrolithiasis and systemic diseases such as hypertension, obesity, dyslipidemia, and insulin resistance. The interplay between these four factors defines metabolic syndrome (MetS). In this review we aim to clarify the associations of MetS and its components to kidney stone incident. Methods: Online databases of EMBASE, MEDLINE, and Google Scholar were searched from January 1998 up to October 2020 to identify observational studies examining the association between metabolic syndrome components and kidney stone incident. Bayesian random-effects meta-analysis and meta-regression were performed to o

SUBMITTER: Rahman IA 

PROVIDER: S-EPMC8577060 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature