AHNAK suppresses ovarian cancer progression through the Wnt/β-catenin signaling pathway.
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ABSTRACT:
SUBMITTER: Cai Y
PROVIDER: S-EPMC8580348 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
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AHNAK suppresses ovarian cancer progression through the Wnt/β-catenin signaling pathway.
Cai Yanlin Y Hu Yi Y Yu Furong F Tong Wenjuan W Wang Shufen S Sheng Shunliang S Zhu Jiayu J
Aging 20211023 20
Globally, ovarian cancer is the 2nd most frequent cause of gynecologic-associated cancer fatalities among women. It has an unfavorable prognosis. There is a need to elucidate on the mechanisms involved in ovarian cancer progression and to identify novel cancer targets. We investigated and verified AHNAK contents in ovarian cancer tissues and corresponding healthy tissues. Then, we overexpressed AHNAK in vitro and in vivo to establish the roles of AHNAK in ovarian cancer cell proliferation and me ...[more]
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