Evidence of bovine leukemia virus circulating in sheep and buffaloes in Colombia: insights into multispecies infection.

ABSTRACT: Bovine leukemia virus (BLV) is the causative agent of leukemia/lymphoma in cattle. However, previous evidence has shown its presence in other species of livestock as well as in humans, suggesting that other species can be accidental hosts of the virus. In viral infections, receptors that are common to different animal species are proposed to be involved in cross-species infections. For BLV, AP3D1 has been proposed to be its receptor, and this protein is conserved in most mammalian species. In Colombia, BLV has been reported in cattle with high prevalence rates, but there has been no evidence of BLV infections in other animal species. In this study, we tested for the virus in sheep (n = 44) and buffaloes (n = 61) from different regions of Colombia by nested PCR, using peripheral blood sampl

SUBMITTER: Olaya-Galan NN 

PROVIDER: S-EPMC8581130 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature