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Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia.

ABSTRACT: Reliable measurement of heating power of magnetic nanofluids (MNs) to accurately predict the AC heat-induction performance in tumors is highly desirable for clinical magnetic nanofluids hyperthermia (MNFH) application because it can save time for screening the performance of newly developed MNFH agent and minimize the over-use of animals dramatically. Here, a bio-mimicking phantom model, called Pseudo-Tumor Environment System (P-TES), biochemically designed by considering the external and internal critical factors related to the complex biological environments is proposed to provide a highly reliable evaluation method of heating performance of MNs for in-vivo MNFH applications. According to the experimentally analyzed results, the heating power of MNs measured using the P-TES is well accorded with the heating temperature measured in the tumors during in-vivo MNFH. This result strongly demonstrates that the proposed P-TES can be recommended as a standardized measurement method of heating performance of MNs for clinical MNFH application.

SUBMITTER: Kim JW

PROVIDER: S-EPMC8586151 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia.

Kim Ji-Wook JW Bae Seongtae S

Scientific reports 20211111 1

Reliable measurement of heating power of magnetic nanofluids (MNs) to accurately predict the AC heat-induction performance in tumors is highly desirable for clinical magnetic nanofluids hyperthermia (MNFH) application because it can save time for screening the performance of newly developed MNFH agent and minimize the over-use of animals dramatically. Here, a bio-mimicking phantom model, called Pseudo-Tumor Environment System (P-TES), biochemically designed by considering the external and intern ...[more]

PMID: 34764326

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Dataset Information

Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia.

Publications

Reliable evaluation method of heating power of magnetic nanofluids to directly predict the tumor temperature during hyperthermia.

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