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ABSTRACT: Introduction
This study was performed to explore the efficacy and safety of pregabalin and gabapentin in patients with spinal cord injury (SCI)-induced neuropathic pain to determine which treatment is most suitable for such patients.Methods
We searched the PubMed, MEDLINE, Embase, and Cochrane Library databases from database inception to August 31, 2020. The quality of the included studies was assessed. We selected the average pain intensity after treatment and the proportion of patients who discontinued treatment because of adverse effects as the outcome indicators for efficacy and safety, respectively. Statistical analyses were performed using Stata, v16.0, and RevMan, v5.3, software.Results
We included eight randomized controlled trials that examined four interve
SUBMITTER: Tong C
PROVIDER: S-EPMC8586377 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature