Association Between the Sulfur Microbial Diet and Risk of Colorectal Cancer.

ABSTRACT:

Importance

Sulfur-metabolizing bacteria that reduce dietary sulfur to hydrogen sulfide have been associated with colorectal cancer (CRC). However, there are limited studies investigating the association between diet and sulfur-metabolizing bacteria in the development of CRC.

Objective

To develop a dietary score that correlates with gut sulfur-metabolizing bacteria and to examine its association with CRC risk.

Design, setting, and participants

This prospective cohort study included data from the Health Professionals Follow-up Study (1986-2014), Nurses' Health Study (1984-2016), and Nurses' Health Study II (1991-2017). Participants were US male health professionals and female registered nurses who were free of inflammatory bowel disease and cancer at baseline, with a su

SUBMITTER: Wang Y 

PROVIDER: S-EPMC8590167 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature