Regularized joint water-fat separation with B₀ map estimation in image space for 2D-navigated interleaved EPI based diffusion MRI.

ABSTRACT:

Purpose

To develop a new water-fat separation and B₀ estimation algorithm to effectively suppress the multiple resonances of fat signal in EPI. This is especially relevant for DWI where fat is often a confounding factor.

Methods

Water-fat separation based on chemical-shift encoding enables robust fat suppression in routine MRI. However, for EPI the different chemical-shift displacements of the multiple fat resonances along the phase-encoding direction can be problematic for conventional separation algorithms. This work proposes a suitable model approximation for EPI under B₀ and fat off-resonance effects, providing a feasible multi-peak water-fat separation algorithm. Simulations were performed to validate the algorithm. In vivo validation was performed

SUBMITTER: Dong Y 

PROVIDER: S-EPMC8596522 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature