Modeled Respiratory Tract Deposition of Aerosolized Oil Diluents Used in Δ⁹-THC-Based Electronic Cigarette Liquid Products.

ABSTRACT: Electronic cigarette, or vaping, products (EVP) heat liquids ("e-liquids") that contain substances (licit or illicit) and deliver aerosolized particles into the lungs. Commercially available oils such as Vitamin-E-acetate (VEA), Vitamin E oil, coconut, and medium chain triglycerides (MCT) were often the constituents of e-liquids associated with an e-cigarette, or vaping, product use-associated lung injury (EVALI). The objective of this study was to evaluate the mass-based physical characteristics of the aerosolized e-liquids prepared using these oil diluents. These characteristics were particle size distributions for modeling regional respiratory deposition and puff-based total aerosol mass for estimating the number of particles delivered to the respiratory tract. Four types of e-liquids w

SUBMITTER: Ranpara A 

PROVIDER: S-EPMC8599147 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature