Ontology highlight
ABSTRACT:
SUBMITTER: Lee JY
PROVIDER: S-EPMC8599657 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Lee Ji Yun JY Oh Il-Young IY Lee Ju-Hyeon JH Kim Seok S Cho Jihoon J Park Charg Hyun CH Yoo Sooyoung S Bang Soo-Mee SM
Scientific reports 20211117 1
Polypharmacy is common in patients with atrial fibrillation (AF), making these patients vulnerable to the occurrence of potential drug-drug interactions (DDIs). We assessed the risk of ischemic stroke and major bleeding in the context of concomitant treatment with potential DDIs in patients with AF prescribed direct oral anticoagulants (DOACs). Using the common data model (CDM) based on an electronic health record (EHR) database, we included new users of DOACs from among patients treated for AF ...[more]