Unknown

Dataset Information

0

Trend analysis of carbapenem-resistant Gram-negative bacteria and antimicrobial consumption in the post-COVID-19 era: an extra challenge for healthcare institutions.


ABSTRACT: The incidence density trend of the carbapenem-resistant Gram-negative bacteria was analysed in device-associated infections and antimicrobial consumption in 99 critical care facilities in a low/middle-income country, between January 2019 and December 2020. Carbapenem-resistant Acinetobacter baumannii (CRAB) per 1000 patient-days increased in 2020 and this finding had a strong positive correlation with the incidence density of COVID-19 by the Spearman test. Polymyxin consumption also increased in 2020 but without significant correlation with CRAB or COVID-19 incidence density, presumably due to empirical and untargeted prescribing as a consequence of concern about CRAB infections. These findings are a warning to infection control programmes and antimicrobial stewardship.

SUBMITTER: de Carvalho Hessel Dias VM 

PROVIDER: S-EPMC8603865 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC2654509 | biostudies-literature
| S-EPMC9241620 | biostudies-literature
| S-EPMC11328053 | biostudies-literature
| S-EPMC10985894 | biostudies-literature
| S-EPMC7649219 | biostudies-literature
| S-EPMC10261712 | biostudies-literature
| S-EPMC8698890 | biostudies-literature
2008-02-26 | GSE7163 | GEO
| S-EPMC6172649 | biostudies-other
| S-EPMC9257860 | biostudies-literature